PLASMA RENIN ACTIVITY; PRA
Renin is a proteolytic enzyme released from juxtaglomerular cells of the kidney. The enzyme cleaves a substrate to produce Angiotensin I which in turn produces Angiotensin II. This metabolite plays a key role in various forms of hypertension. Increased levels are seen in Renal hypertension, Addison’s disease and Secondary hypoaldosteronism. Low levels are detected in Hyporeninemic hypoaldosteronism and Primary aldosteronism |
![]() Pre-test Information : Overnight fasting is preferred. Patient should be ambulatory or upright 2 hours prior to the test. No medication 3 weeks prior to draw is recommended |
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![]() Report Delivery : Same day |
PLASMA RENIN ACTIVITY; PRA
Test Code | P-18 |
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Test Description | **PLASMA RENIN ACTIVITY; PRA |
Clinical Category | KIDNEY DISORDERS |
Sample | 3 mL (2.5 mL min.) plasma IN EDTA tube. Collect blood between 8 am to 10 am. Patient should be ambulatory / upright 2 hours prior to the test. Overnight fasting is preferred |
Method/Technology | CLIA |
Storage/Temp | |
Reporting Time | DAILY |